Abstract

Case Report

Diffuse large B-cell Lymphoma mimicking as cholangiocarcinoma in a young male presenting with obstructive jaundice

Muhammad Danish*, Shoaib Ahmed Khan, Dilnawaz Samoon, Zain Majid, Farina Hanif, Abbas Ali Tassneem and Nasir Hasan Luck

Published: 12 October, 2021 | Volume 5 - Issue 1 | Pages: 039-040

The involvement of bile duct in lymphoma is considered to be very rare and is usually a sequela of a disseminated disease [1]. In contrast to secondary involvement, primary non-Hodgkin’s lymphoma arising from the bile duct is extremely rare and presents with obstructive jaundice [2,3]. Non-Hodgkin’s lymphoma (NHL) accounts for 1% - 2% of all cases of malignant biliary obstruction [4]. Hepatobiliary involvement by malignant lymphoma is usually a secondary manifestation of systemic lymphoma. The first case of Non-Hodgkin lymphoma arising from bile duct was described by Nguyen in 1982 [5]. Most common extra nodal involvement of NHL is abdomen. Although, involvement of the stomach, pancreas or common bile duct is not common [6]. We present to you a case of 31year old male who presented to us with obstructive jaundice and was later diagnosed as Diffuse Large B-Cell lymphoma.

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References

  1. Kang CS, Lee YS, Kim SM, Kim BK. Primary low grade B cell lymphoma of mucosa associated lymphoid tissue type of the common bile duct. J Gastroenterol Hepatol. 2001; 16: 949-951. PubMed: https://pubmed.ncbi.nlm.nih.gov/11555119/
  2. Joo YE, Park CH, Lee WS, Kim HS, Choi SK, et al. Primary non-Hodgkin’s lymphoma of the common bile duct presenting as obstructive jaundice. J Gastroenterol. 2004; 39: 692-696. PubMed: https://pubmed.ncbi.nlm.nih.gov/15293142/
  3. Eliason SC, Grosso LE. Primary biliary malignant lymphoma clinically mimicking cholangiocarcinoma: a case report and review of the literature. Ann Diagn Pathol 2001; 5: 25-33. PubMed: https://pubmed.ncbi.nlm.nih.gov/11172204/
  4. Lokich JJ, Kane RA, Harrison DA, McDermott WV. Biliary tract obstruction secondary to cancer: management guidelines and selected literature review. J Clin Oncol. 1987; 5: 969-981. PubMed: https://pubmed.ncbi.nlm.nih.gov/3295131/
  5. Nguyen GK. Primary extranodal non-Hodgkin’s lymphoma of the extrahepatic bile ducts. Report of a case. Cancer. 1982;50: 2218-2222. PubMed: https://pubmed.ncbi.nlm.nih.gov/7127262/
  6. Yang T, Pan J, Zou Y. Obstructive Jaundice caused by Non-Hodgkin Lymphoma in common bile duct. J Pediatr. 2015; 167: 1168-1168. PubMed: https://pubmed.ncbi.nlm.nih.gov/26340876/
  7. Swerdlow SH, Campo E, Harris NL, et al. World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2008
  8. Kallab A. Diffuse large B cell lymphoma. Medscape. 2013
  9. Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, et al. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood. 2006; 107: 265-276. PubMed: https://pubmed.ncbi.nlm.nih.gov/16150940/
  10. Armitage JO, Weisenburger DD. New approach to classifying non-Hodgkin’s lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin’s Lymphoma Classification Project. J Clin Oncol. 1998; 16: 2780-2795. PubMed: https://pubmed.ncbi.nlm.nih.gov/9704731/
  11. Coiffier B. State-of-the-art therapeutics: diffuse large B cell lymphoma. J Clin Oncol. 2005; 23: 6387–6393. PubMed: https://pubmed.ncbi.nlm.nih.gov/16155024/
  12. Birrer MJ, Young RC. Differential diagnosis of jaundicein lymphoma patients. Semin Liver Dis. 1987; 7: 269–277. PubMed: https://pubmed.ncbi.nlm.nih.gov/3317863/
  13. Feller E, Schiff Man FJ. Extrahepatic biliary obstruction by lymphoma. Arch Surg. 1990; 125: 1507–1509. PubMed: https://pubmed.ncbi.nlm.nih.gov/2241566/
  14. Rosenberg SA, Diamond HD, Jaslowitz B, Craver LD. Lymph sarcoma: a review of 1269 cases. Medicine. 1961; 40: 31–84. PubMed: https://pubmed.ncbi.nlm.nih.gov/13743408/
  15. Yoon MA, Lee JM, Kim SH, Lee JY, Han JK, et al. Primary biliary lymphoma mimicking cholangiocarcinoma: a characteristic feature of discrepant CT and direct cholangiography findings. J Korean Med Sci. 2009; 24: 956–959. PubMed: https://pubmed.ncbi.nlm.nih.gov/19794999/

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